Tear Osmolarity Testing and the Contact Lens Patient

tear osmolarity testing protocol dave geffen.fwIn the latest edition of ‘In My Practice’, Dr. David Geffen explains how Tear Osmolarity Testing can be a great asset for contact lens patients. Due to the dry eye symptoms and discomfort contact lenses can cause, patients who wear them are being forced to give up on their lenses all together more and more often. Dr. Geffen believes that Tear Osmolarity Testing can help to better determine the course of treatment for these patients and, in turn, keep them wearing their contacts comfortably.

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Antioxidant and Inflammatory Cytokine in Tears of Patients with Dry Eye Syndrome Treated with Preservative-free Versus Preserved Eye Drops

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In the busy rush of daily practice, we sometimes forget about the importance of non preserved (NP) or Preservative-free (PF) drops for our dry eye disease (DED) patients. In the July 2014 volume of Investigative Ophthalmology and Vision Science … [Continue reading]

An Indispensable Guide to Dry Eye Disease

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The Ocular Surface Journal recently published what Dr. Michael Lemp is calling an indispensable guide to a new understanding of Dry Eye Disease. Entitled 'Rethinking Dry Eye Disease: A Perspective on Clinical Implications', Lemp adds that the … [Continue reading]

Topical Administration of Lacritin is a Novel Therapy for Aqueous-deficient Dry Eye Disease.

Optometry concept

While we continue to search for a new therapeutic drug for our dry eye disease (DED) patients to be approved by the FDA, another potential prospect emerges from a new research endeavor by Vijmasi et al found in Investigative Ophthalmology and Vision … [Continue reading]

Longitudinal Changes in Tear Fluid Lipidome Brought About by Eyelid-warming Treatment in a Cohort of Meibomian Gland Dysfunction

Close-up of a beautiful blond wearing an eye mask

Simple things we can offer our patients many times result in significant benefit. We know meibomian gland dysfunction (MGD) is a leading cause of evaporative dry eye and ocular discomfort characterized by an unstable tear film principally attributed … [Continue reading]

Tracking Tear Osmolarity Numbers from Visit to Visit and the Importance of This Information for Our Patients

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In her fourth article for the Dry Eye Review, Dr. Cynthia Matossian covers the importance of educating and communicating with patients about their dry eye symptoms as well as lifestyle habits during each visit. Matossian also stresses that patient … [Continue reading]

Hyperosmolar Tears Enhance Sensitivity of the Special Corneal Nerves to Ocular Surface Cooling: Possible Neural Basis for Cold-induced Dry Eye Pain

cold air

"Tear hyperosmolarity is a ubiquitous feature of dry eye disease” according to the Aug. 25, 2014 Recently Accepted Papers Alert of Investigative Ophthalmology & Visual Science (IOVS). Harumitsu et al provide extremely interesting evidence in the … [Continue reading]

What Do We Do with the Information We Obtain from Tear Osmolarity Testing

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In Dr. Cynthia Matossian's third installment of 'In My Practice', she focuses on the process that occurs after she has obtained a patient's tear osmolarity data. From educating the patient, to treatment recommendations, Dr. Matossian elaborates on … [Continue reading]

Comparative Role of 20% Cord Blood Serum and 20% Autologous Serum in Dry Eye with Hansen’s Disease

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While we wait for more effective topical ophthalmic pharmaceutical drugs for the treatment of significant dry eye disease (DED) in patients that currently available prescription therapy is insufficient, we should not forget the importance of using … [Continue reading]

Rigel Dry Eye Drug Misses Endpoints in Phase 2


Well, another dry eye disease (DED) drug fails to meet endpoints. Rigel Pharmaceuticals Inc. announced its JAK/SYK inhibitor (R348) did not meet the primary or secondary endpoints in their Phase 2 clinical study. The endpoints were measured by … [Continue reading]